Shift work as an oxidative stressor

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Shift work as an oxidative stressor

BACKGROUND Some medical disorders have higher prevalence in shift workers than others. This study was designed to evaluate the effect of night-shift-working on total plasma antioxidant capacity, with respect to the causative role of oxidative stress in induction of some of these disorders. METHODS Two blood samples were taken from 44 workers with a rotational shift schedule, one after their d...

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Salt is an oxidative stressor for gastric epithelial cells.

Salt/NaCl has been reported to induce necrosis in gastric mucosal cells, however, the mechanisms for gastric injury by salt are not clarified. In this study, we elucidated whether salt is an oxidative stress inducer via mitochondrial injury on rat gastric epithelial cells (RGM-1) in 300, 450, 650 and 1000 mM of NaCl-contained medium. To clarify whether salt-induced reactive oxygen species (ROS)...

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Acetaldehyde is an oxidative stressor for gastric epithelial cells

Alcohol drinking and smoking contain the risk of a carcinogenesis. Acetaldehyde is content in cigarette smoke and an ethanol metabolite. However the clear evidence for reactive oxygen species (ROS) generation by acetaldehyde in gastric cells in vitro is none. In this study, we elucidated acetaldehyde is an oxidative stress inducer on rat gastric epithelial cells by electron paramagnetic resonan...

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Exposure to shift work as a risk factor for diabetes.

Using telephone survey data from 1111 retired older adults (≥65 years; 634 male, 477 female), we tested the hypothesis that exposure to shift work might result in increased self-reported diabetes. Five shift work exposure bins were considered: 0 years, 1-7 years, 8-14 years, 15-20 years, and >20 years. Shift work exposed groups showed an increased proportion of self-reported diabetes (χ(2) = 22...

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Commentary: Metabolic syndrome as a result of shift work exposure?

women. Am J Epidemiol 2007;165:175–83. 21 Sakata K, Suwazono Y, Harada H et al. The relationship between shift work and the onset of hypertension in male Japanese workers. J Occup Environ Med 2003;45:1002–06. 22 Oishi M, Suwazono Y, Sakata K et al. A longitudinal study on the relationship between shift work and the progression of hypertension in male Japanese workers. J Hypertens 2005;23:2173–7...

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ژورنال

عنوان ژورنال: Journal of Circadian Rhythms

سال: 2005

ISSN: 1740-3391

DOI: 10.1186/1740-3391-3-15